The dynamics of conflict in the Middle East involve many complex factors that interact with each other. Large countries such as the United States, Russia and China play an important role in influencing the direction of this conflict. In the Middle East region, strategic, economic and political interests are the main drivers for the involvement of major countries. For example, the United States has historical ties with Israel and supports various security initiatives in the region. This support does not only take the form of military assistance, but also in the form of intelligence and sophisticated technology. In addition, Washington has military bases in countries such as Saudi Arabia and Qatar, which makes it a key player in responding to security situations. On the other hand, Russia took a different approach by supporting the Bashar al-Assad regime in Syria. The existence of military bases in Tartus and Hmeimim shows Moscow’s commitment to maintaining its influence in the area. Russia is also active in the diplomatic process, seeking to be a mediator more visible to Arab countries. One example is Russia’s involvement in the negotiation process regarding the conflicts in Yemen and Syria. Meanwhile, China is showing increasing interest in the Middle East, especially through the Belt and Road initiative. With large investments in infrastructure, Beijing is seeking to strengthen its economic ties in the region, including in the energy sector. Although China is not as militarily involved as the US and Russia, its economic influence continues to grow, widening the reach of its strategic interests. The rise of non-state militia groups, such as Hezbollah in Lebanon and Hamas in Gaza, further complicates the dynamics of the conflict. Major countries are often involved in supporting or opposing these groups, depending on their interests. For example, Iran provides military and financial support to Hezbollah, while the US considers it a threat that must be dealt with. The changing geopolitical climate is also creating new challenges. New alliances emerged, such as the Abraham Accords between Israel and the Gulf states. This shows how the strategies of major countries can adapt to the latest dynamics in the region. This process of normalizing relations, although positive, still leaves tensions with Iran, which feels isolated. Economic sanctions have also become a major political tool for large countries. For example, sanctions against Iran aim to limit its nuclear program, but also impact the economies of other countries in the region. Many countries feel pressured between economic interests and political pressure from the US. Finally, social media and information technology play a crucial role in this new form of conflict. Propaganda and information can spread quickly, influencing public opinion and changing the dynamics of conflict. Large powers often utilize these channels to promote narratives that suit their interests. With all these factors, the dynamics of conflict in the Middle East continue to develop. The existence of large countries in this region shows how complex the issues involved are and the importance of a deep understanding of their interactions. This creates new challenges and opportunities for resolution, depending on how major powers navigate conflicting interests and conflicts.